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David Watson's avatar

My doc prescribed B12 supplement to treat insulin resistance. I take Methylguard, a methylated form that improves absorbtion. I have an ApoE4 mutation that disrupts processing so we're keeping my blood levels of B12 very high. My insulin resistance has pretty much resolved, along with improved diet, and my homocystene decreased, but remains a little higher than I want, so I'm increasing weightlifting exercise to work on that. So many variables.

I was on two statins and had worsening cardiovascular "disease" which I have reversed with diet and lifestyle changes. I'm off the statins, but still take a coq10 supplement, just in case. They're cheap. I get blood tests several times a year, and my coq10 levels only normalized when I cut the carbs. Carb overdoses is the root of many epidemics.

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TnDoc's avatar

You have a great doc. A keeper.

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Leo's avatar

A doc who prescribed statins = "a great doc?"

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TnDoc's avatar

I have no idea who prescribed the statins,. Prescribing B12 is what I keyed on. The odds of that happening are tiny.

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David Watson's avatar

Great docs are never perfect.

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TnDoc's avatar

Exactly... and, they are comfortable with that. The worst pf the profession are "perfect" - Dr. Fauci being a shining example.

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David Watson's avatar

Perfection is more imortant for patients who are entirely dependent on their docs. I treat mine as partners at best, usually as employees. They have a job to do and need varying amounts of supervision. But the results are entirely my responsibility.

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cricket1776's avatar

I take PQQ (PyrroloQuinoline Quinone) with Coq10 because this encourages mitochodrial regrowth inside the cells. My dentist told me about this. After my open heart surgery (2009), my eject fraction was 45%. Normal is 55% - 60%. A month ago it measured 53%, so I think the PQQ - Coq10 works. I am also diabetic. Recently I stopped eating grains, but still eat fruit and resistant starch vegetables like peas and beans. It helps my blood sugar. You may want to check into this.

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David Watson's avatar

Looks interesting. Thanks. I'll study that some more. Like most supplements, apparently it's available with fruits and vegetables, so a good diet should provide whatever we need. But sometimes, more is better, so it's always worth a look.

I assume you've read Esselstyn. He has successfully treated heart patients, even reversing fairly serious conditions, with very low fat diet. No oils, nothing with a mother. If the muscle itself is damaged, apparently that won't heal, but function can be improved with diet and lifestyle, as you have seen. I followed his guidance, monitored by a live cardiologist, for 2 years. Lost a lot of weight (BMI 30 to 20), heart condition improved a lot, still had some problems, but much less. The biggest change for me was ditching carbs. That maintained my prior gains and cleaned up the other labs. The theory that seemed to work for me was described by Saladino in Carnivore Code.

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TnDoc's avatar

Thanks, will invedtigate.

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MichelleD's avatar

You’re right- so many variables!

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CW's avatar

wondering if phenylalanine/tyrosine makes sense for increased coq10 synthesis, le Chatelier

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TnDoc's avatar

I have no idea. Of course, watch phenylalanine use if potential/history of PKU.

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